Azithromycin

Composition:
Azirox™ 500 Tablet: Each film coated tablet contains Azithromycin Dihydrate USP equivalent to  Azithromycin 500 mg. Azirox™ Powder for Suspension (20 ml, 35 ml & 50 ml): Each 5 ml reconstituted suspension contains Azithromycin Dihydrate USP equivalent to Azithromycin 200 mg. Pharmacology  Azirox™ (Azithromycin) is an azalide antibiotic active against Gram-positive and Gram-negative organisms.  Azirox™ (Azithromycin) acts by binding to the 50S ribosomal subunit of susceptible organisms & thus interferes with microbial protein synthesis. 

Indication:
Acute bacterial exacerbations of chronic obstructive pulmonary disease, Communityacquired pneumonia,  Acute otitis media, Sinusitis, Pharyngitis, Tonsillitis, Skin and soft tissue infections, Urethritis and Cervicitis, Genital ulcer disease, Sexually transmitted diseases (STD), Typhoid fever. 

Dose and Administration:
Adult dose: For Acute bacterial exacerbations of chronic obstructive pulmonary disease, community-acquired pneumonia, sinusitis, pharyngitis, tonsillitis and Skin and Soft tissue infections due to the indicated organisms: 500 mg once daily orally for 3 days or as an alternative given over 5 days with 500 mg dose on the first day followed by 250 mg once daily on days 2 through 5. Genital ulcer disease, non-gonococcal urethritis and cervicitis: 1 g (1000 mg) as a single dose. Urethritis and cervicitis due to Neisseria Gonorrhoeae: 2g (2000 mg) as a single dose. Sexually transmitted diseases: 1 g as a single dose. 

Typhoid fever: 500 mg once daily for 7 days. Pediatric dose: For children over 6 months recommended dose is 10mg/kg once daily for 3 days 15-25 kg: 200 mg once daily for 3 days, 26-35 kg: 300 mg once daily for 3 days, 36-45 kg : 400 mg once daily for 3 days, Azirox™ should be taken at least 1 hour before or 2 hour after meal or as directed by the physician.