Human Health Division (HHD) Products

Veterinary Division (VET)
Product List by Generic Name
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Amlodipine + Atenolol

Composition
CVnor A: Each tablet contains Amlodipine Besilate BP equivalent to
Amlodipine 5 mg and Atenolol BP 50 mg.

Pharmacology
CVnor A is a fixed dose combination of Amlodipine and Atenolol. Amlodipine
is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of
calcium ions into vascular smooth muscle and cardiac muscle; it has a greater
effect on vascular smooth muscle cells than cardiac muscle cells. Amlodipine is
a peripheral vasodilator that acts directly on vascular smooth muscle to cause a
reduction in peripheral vascular resistance and reduction in blood pressure.
Amlodipine reduces tone, decreases coronary vasoreactivity and lowers
cardiac demand by reducing after load. Atenolol is a cardio-selective beta-blocker. It does not possess any membrane-stabilizing action. The cardio selectivity is dose related. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS. Atenolol also causes a reduction in myocardial oxygen
demand by virtue of its negative inotropic and negative chronotropic effect.

Indication
Hypertension is not controlled by monotherapy, patients with angina pectoris and hypertension as co-existing diseases; post myocardial infarction, refractory angina pectoris where nitrate therapy has failed.

Dose & Administration
Initially, 1 tablet daily. If necessary, the dose may be increased to 2 tablets daily.
Elderly patients or patients with hepatic impairment ½ tablet daily. The dosage,
however, should be individualized or as directed by the physician.

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Ascorbic Acid

Administration:
Maybe taken with or without food

Mode of Action

Vitamin C: Necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.

Precaution

Should be given with caution to patient with hyperoxaluria.

Side Effect

Flushing, Flank pain, Faintness, headache, Diarrhea, dyspepsia, nausea, vomiting, Hyperoxaluria (large doses)

Interaction

Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.

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Amorolfine

Composition:
Curafin Cream: Each gram cream contains Amorolfine Hydrochloride BP equivalent to Amorolfine 2.5 mg.

Indication:
Curafin Cream is indicated for the treatment of Tinea pedis (athlete's foot), Tinea cruris, Tinea inguinalis,Tinea corporis,Tinea manuum & Pityriasis versicolor.

Dose & Administration:
To be applied to affected skin areas once daily following cleansing (in the evening).The treatment should be continued without interruption until clinical cure, and for 3 -5 days
thereafter. The required duration of treatment depends on the species of fungi and on the localization of the infection. In general, treatment should be continued for at least two 
to three weeks. With foot mycoses, up to six weeks of therapy may be necessary or as directed by the physicians

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Ambroxol

Composition:

BroxTM syrup: Each 5 ml syrup contains Ambroxol Hydrochloride BP 15 mg.

BroxTM paediatric drops: Each ml contains Ambroxol Hydrochloride BP 6 mg.


Indication:

Productive cough

Acute and chronic diseases of respiratory tracts associated with

viscid mucus including acute and chronic bronchitis.

Inflammatory diseases of rhinopharyngeal tract (e.g. laryngitis,pharyngitis, sinusitis and rhinitis) associated with viscid mucus.

Asthmatic bronchitis, bronchial asthma with difficult departure of mucus

Bronchiectasis

Chronic pneumonia


Dose & Administration:

Average daily dose (preferably after meal):

Brox Paediatric Drops

0-6 months: 0.5 ml 2 times a day

6-12 months: 1 ml 2 times a day

1-2 years: 1.25 ml 2 times a day

Brox Syrup

2-5 years old: 2.5 ml (1/2 teaspoonful) 2-3 times a day

5-10 years old: 5 ml (1 teaspoonful) 2-3 times a day

Above 10 years old: 10 ml (2 teaspoonful) 3 times a day

Or as directed by the physician

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Alogliptin

Composition
Aloglip 6.25 Tablet: Each film coated tablet contains Alogliptin Benzoate INN equivalent to Alogliptin 6.25 mg.
Aloglip 12.5 Tablet: Each film coated tablet contains Alogliptin Benzoate INN equivalent to Alogliptin 12.5 mg.
Aloglip 25 Tablet: Each film coated tablet contains Alogliptin Benzoate INN equivalent to Alogliptin 25 mg.

Indication
Aloglip is indicated as an adjunct to diet and exercise to improve glycaemic control in adults with type-2 diabetes mellitus.

Dose & Administration
The recommended dose in patients with normal renal function or mild renal impairment is 25 mg once daily or as directed by the physicians.


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Azithromycin

Composition:
Azirox™ 500 Tablet: Each film coated tablet contains Azithromycin Dihydrate USP equivalent to  Azithromycin 500 mg. Azirox™ Powder for Suspension (20 ml, 35 ml & 50 ml): Each 5 ml reconstituted suspension contains Azithromycin Dihydrate USP equivalent to Azithromycin 200 mg. Pharmacology  Azirox™ (Azithromycin) is an azalide antibiotic active against Gram-positive and Gram-negative organisms.  Azirox™ (Azithromycin) acts by binding to the 50S ribosomal subunit of susceptible organisms & thus interferes with microbial protein synthesis. 

Indication:
Acute bacterial exacerbations of chronic obstructive pulmonary disease, Communityacquired pneumonia,  Acute otitis media, Sinusitis, Pharyngitis, Tonsillitis, Skin and soft tissue infections, Urethritis and Cervicitis, Genital ulcer disease, Sexually transmitted diseases (STD), Typhoid fever. 

Dose and Administration:
Adult dose: For Acute bacterial exacerbations of chronic obstructive pulmonary disease, community-acquired pneumonia, sinusitis, pharyngitis, tonsillitis and Skin and Soft tissue infections due to the indicated organisms: 500 mg once daily orally for 3 days or as an alternative given over 5 days with 500 mg dose on the first day followed by 250 mg once daily on days 2 through 5. Genital ulcer disease, non-gonococcal urethritis and cervicitis: 1 g (1000 mg) as a single dose. Urethritis and cervicitis due to Neisseria Gonorrhoeae: 2g (2000 mg) as a single dose. Sexually transmitted diseases: 1 g as a single dose. 

Typhoid fever: 500 mg once daily for 7 days. Pediatric dose: For children over 6 months recommended dose is 10mg/kg once daily for 3 days 15-25 kg: 200 mg once daily for 3 days, 26-35 kg: 300 mg once daily for 3 days, 36-45 kg : 400 mg once daily for 3 days, Azirox™ should be taken at least 1 hour before or 2 hour after meal or as directed by the physician.

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