Methenamine Hippurate
Composition
Methebac Tablet: Each tablet contains Methenamine Hippurate USP 1 g.
Indications
Methebac is indicated for prophylactic or suppressive treatment of
frequently recurring urinary tract infections when long-term therapy is
considered necessary. This drug should only be used after eradication
of the infection by other appropriate antimicrobial agents.
Dosage & Administration
1 tablet (1.0 g) twice daily (morning and night) for adults and paediatric
patients over 12 years of age. 1/2 to 1 tablet (0.5 to 1.0 g) twice daily
(morning and night) for paediatric patients 6 to 12 years of age. Since the
antibacterial activity of Methebac is greater in acid urine, restriction of
alkalinizing foods and medications is desirable or as directed by the
physician
Meropenem
Composition
InpenTM 500 mg IV injection: Each vial contains Meropenem USP 500 mg.
InpenTM 1 g IV injection: Each vial contains Meropenem USP 1 g.
Indications
InpenTM is indicated for treatment, in adults and children, of the following infections caused by single or multiple susceptible bacteria and as empiric therapy prior to the
identification of the causative organisms:
Lower Respiratory Tract Infections, Urinary Tract Infections, including complicated infections Intra-abdominal Infections, Gynaecological infections, including
postpartum infections, Skin and Skin Structure Infections, Meningitis, Septicaemia, Empiric treatment, including initial monotherapy, for presumed bacterial
infections in host-compromised, neutropenic patient.
Because of its broad spectrum or bactericidal activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. InpenTM is effective for the treatment of
polymicrobial infections.
Dosage and Administration
ADULTS:
Usual dose: 500 mg to 1 g by intravenous administration every 8 hours depending on type end severity of Infection.
Exceptions: 1. Febrile episodes to neutropenic patients - the dose should be I g every 8 hours. 2. Meningitis- the dose should be 2 g every 8 hours.
As with other antibiotic, caution may be required in using Meropenem as monotherapy in critically iII patients with known or suspected Pseudomonas aeruginosa lower
respiratory tract erections. Regular sensitivity testing is recommended when treating Pseudomonas aeruginosa infections.
InpenTM should be given as an intravenous bolus injection over approximately 5 minutes or by intravenous infusion over approximately 15 to 30 minutes (see Method of
Administration).
ELDERLY
No dosage adjustment is required for the elderly with normal renal function or creatinine clearance values above 50 ml/min.
CHILDREN
For infants and children over 3 months and up to 12 years of age the recommended intravenous dose is 10 to 40 mg/kg every 8 hours depending on type and severity of
infection, the known or suspected susceptibility of the pathogen(s) and the condition of the patient. In children over 50 kg weight, adult dosage should be used
Mometasone Furoate
Composition
Momespray: Each spray delivers Mometasone Furoate BP 50 mcg.
Pharmacology
Momespray is a corticosteroid demonstrating
anti-inflammatory properties. The precise mechanism of
corticosteroid action on allergic rhinitis is not known.
Corticosteroids have been shown to have a wide range of
effects on multiple cell types (e.g, mast cells, eosinophils,
neutrophils, macrophages, and lymphocytes) and
mediators (e.g, histamines, eicosanoids, leukotrienes,
and cytokines) involved in inflammation. Protein binding
for Mometasone Furoate was reported to be 98% to 99%
in concentration range of 5 to 500 ng/ml.The effective
plasma elimination half-life of Mometasone Furoate is 5.8
hours.
Indication
Momespray is indicated for the treatment of the nasal
symptoms of seasonal and perennial allergic rhinitis, in
adults and pediatric patients 2 years of age and older. It
is indicated for the prophylaxis of the nasal symptoms of
seasonal allergic rhinitis in adult and adolescent patients
12 years and older. It is also indicated for the treatment of
nasal polyps in patients 18 years and older.
Dosage & Administration
Administer Mometasone Nasal Spray by the intranasal
route only.
Allergic Rhinitis
Adults and Children 12 Years of Age and Older: For
prophylaxis and treatment of the nasal symptoms of seasonal allergic rhinitis and treatment of the nasal symptoms of perennial allergic rhinitis use two sprays (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 mcg). In patients with a known seasonal allergen that precipitates nasal symptoms of seasonal allergic rhinitis, prophylaxis use
Momespray 50 mcg (200 mcg/day) 2 to 4 weeks prior to the anticipated start of the pollen season.
Children (2 to 11 years of age)
For treatment of the nasal symptoms of seasonal and perennial allergic rhinitis use one spray (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 mcg).
Nasal Polyps
Adults 18 years of Age and Older: For nasal polyps use two sprays (50 mcg of Mometasone Furoate in each spray) in each nostril twice daily (total daily dose of 400 mcg). A dose of two sprays (50 mcg of mometasone furoate in each spray) in each nostril once daily (total daily dose of 200 mcg) is also effective in some patients or as directed by the physician.
Magnesium Oxide
Indications
Magnesium Oxide is indicated in-
- Relieving the symptoms of magnesium deficiency.
- Rapid or irregular heart rate, heart attack, angina pectoris, mild or severe hypertension.
- Tetania, muscle cramp, gastrointestinal cramps, stress, increased stimulability of muscles and nerves, call cramps, and cramp in newborn and young children.
- Gynecological diseases, cervical insufficiency, eclampsia, pre-eclampsia, tocolysis, dysmenorrhea.
- Calcification and ossification
- Prevention of kidney stone formation
- Diabetes treatment and migraine
Pharmacology
Magnesium belongs to the group of drugs called mineral support products. It occurs in nature in the form of the mineral periclase. Magnesium is required for energy production, oxidative phosphorylation, and glycolysis. In its purest form, magnesium oxide is a colorless or white crystalline material or very fine powder, with no odor and a bitter taste.
Magnesium helps to regulate diverse biochemical reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It contributes to the structural development of bone and is required for the synthesis of DNA, RNA, and the antioxidant glutathione. Magnesium also plays a role in the active transport of calcium and potassium ions across cell membranes, a process that is important to nerve impulse conduction, muscle contraction, and normal heart rhythm.
Excretion
The majority of magnesium is excreted renally.
Dosage & Administration
The recommended daily dose for adults and adolescents (12-17 years) is 1-2 tablets.
Interaction
Aminoquinolones, Nitrofurantoin, Penicillamine, Tetracyclines, Fluoroquinolones, Digoxin, Lithium, Sodium polystyrene sulfonate, Nifedipine etc.
Contraindications Hypersensitivity and severe renal impairment.
Side Effects
- Stomach upset and diarrhea
- Hypermagnesaemia
- Paralytic ileus
- Hyper-excitability
- Muscle weakness
- Sleepiness
Pregnancy & Lactation
It should be used as directed by the physician during pregnancy and lactation.
Precautions & Warnings
Before taking a magnesium supplement, tell your doctor or pharmacist if you are allergic to it.
Overdose Effects
Symptoms of overdose may include slow heartbeat, severe dizziness, confusion, muscle weakness, loss of consciousness, diarrhea and hypermagnesemia.
Therapeutic Class
Antacids, Electrolytes preparations, Oral electrolytes preparations
Storage Conditions
Keep out of reach of children. Store in a dry place, below 25°C temperature, and protected Irom light.
Multivitamin & Multimineral A-Z Gold Preperation
Adult Dose:
Oral Adult 3 multivitamin multimineral with complete antioxidant Tablet: 1 tablet once daily or as recommended by the physician.
Child Dose:
Safety & Efficacy has not been established..
Contraindications: Patients with a known hypersensitivity to any of the ingredients.
Precautions & warnings: Should not use in over dosage. Patients with mild to moderate renal failure. Diabetes, patients prone to recurrent renal calculi. Long term intake of high levels of vitamin A (Excluding that sourced from Beta carotene) may increase the risk of osteoporosis in postmenopausal women. Do not take this product if taking other vitamin A supplements. Folic acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematological remission can occur while neurological manifestations remain progressive.
Pregnancy & Lactation : Pregnancy Category Not Classified FDA has not yet classified the drug into a specified pregnancy category.
Interaction : There are no known drug interactions and none documented.
Multivitamin & Multimineral A-Z Gold Preperation
Adult Dose:
Oral Adult 32 multivitamin multimineral with complete antioxidant Tablet: 1 tablet daily or as recommended by the physician.
Child Dose:
Safety & Efficacy has not been established..
Contraindications: Patients with a known hypersensitivity to any of the ingredients.
Precautions & warnings: Should not use in over dosage. Patients with mild to moderate renal failure. Diabetes, patients prone to recurrent renal calculi. Long term intake of high levels of vitamin A (Excluding that sourced from Beta carotene) may increase the risk of osteoporosis in postmenopausal women. Do not take this product if taking other vitamin A supplements. Folic acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematological remission can occur while neurological manifestations remain progressive.
Pregnancy & Lactation : Pregnancy Category Not Classified FDA has not yet classified the drug into a specified pregnancy category.
Interaction : There are no known drug interactions and none documented.
Multivitamin & Multimineral A-Z Gold Preperation
Adult Dose:
Oral Adult 32 multivitamin multimineral with complete antioxidant Tablet: 1 tablet daily or as recommended by the physician.
Child Dose:
Safety & Efficacy has not been established..
Contraindications: Patients with a known hypersensitivity to any of the ingredients.
Precautions & warnings: Should not use in over dosage. Patients with mild to moderate renal failure. Diabetes, patients prone to recurrent renal calculi. Long term intake of high levels of vitamin A (Excluding that sourced from Beta carotene) may increase the risk of osteoporosis in postmenopausal women. Do not take this product if taking other vitamin A supplements. Folic acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematological remission can occur while neurological manifestations remain progressive.
Pregnancy & Lactation : Pregnancy Category Not Classified FDA has not yet classified the drug into a specified pregnancy category.
Interaction : There are no known drug interactions and none documented.
Multivitamin+ Codliver Oil
Description:
RevamTM kidssyrup is a balanced combination of eight essential vitamins and cod liver oil which adequately replenish the deficiency of vitamin and supports proper growth and healthy development of children.
RevamTM kids syrup contains cod liver oil which is the nature's most abundant sources of vitamin A and D. It is also particularly rich source of rare eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) which make up the important omega-3 essential fatty acids. They help
maintain a healthy blood circulation by lowering serum triglyceride levels and reducing the tendency for blood to clot. Besides keeping the body fit and healthy, it also builds resistance for infections, such as cough, cold, chest and bronchial troubles
Indication:
RevamTM Kids syrup is indicated for the treatment and prevention of vitamin deficiencies with restricted diets, improper food intake and decreased absorption. It is also indicated in children with increased
requirement of vitamins due to acute and chronic disease, vitamin lacking symptoms for growing child, lack of appetite, including patients under rehabilitating period.
Dosage and Administration:
Infants (1-12 months): 1/2 tea spoon full (2.5 ml) daily
Child (1-4 years): 1 tea spoon full (5 ml) daily
Child (Above 4 years): 11/2 tea spoon full (7.5 ml) daily
Adult: 2 tea spoon full (10 ml) daily
Momeasone
Composition:
Momespray™: Each spray contains Mometasone Furoate BP 50 meg.
Indication:
Momespray™ is indicated for the treatment of the nasal symptoms of seasonal and perennial allergic rhinitis, in adults and pediatric patients 2 years of age and older. It
is indicated for the prophylaxis of the nasal symptoms of seasonal allergic rhinitis in adult and adolescent patients 12 years and older. It is also indicated for the treatment of
nasal polyps in patients 18 years and older.
Dose & Administration:
Administer Mometasone Nasal Spray by the intranasal route only.
Allergic Rhinitis
Adults and Children 12 Years of Age and Older: For prophylaxis and treatment of the nasal symptoms of seasonal allergic rhinitis and treatment of the nasal
symptoms of perennial allergic rhinitis use two sprays (50 meg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 meg). In patients
with a known seasonal allergen that precipitates nasal symptoms of seasonal allergic rhinitis, prophylaxis use Momespray™ 50 meg (200 meg/day) 2 to 4 weeks prior
to the anticipated start of the pollen season.
Children (2 to 11 years of age) For treatment of the nasal symptoms of seasonal and perennial allergic rhinitis use one spray (50 meg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 meg).
Nasal Polyps
Adults 18 years of Age and Older: For nasal polyps use two sprays (50 meg of Mometasone Furoate in each spray) in each nostril twice daily (total daily dose of 400
meg). A dose of two sprays (50 meg of mometasone furoate in each spray) in each nostril once daily (total daily dose of 200 meg) is also effective in some patients.
Metformine
Composition:
NVmet™ 500 Tablet: Each film coated tablet contains Metformin Hydrochloride BP 500 mg.
NVmet™ 850 Tablet: Each film coated tablet contains Metformin Hydrochloride BP 850 mg.
NVmet™ 500 SR Tablet: Each sustained release tablet contains Metformin Hydrochloride BP 500 mg.
Indication:
NVmet™, as monotherapy, is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes. NVmet™ is also indicated for use in combination with other agents, that do not result in adequate glycemic control.
Dose and administration:
Diabetes mellitus: Adult and child over 10 years initially 500 mg with breakfast for at least 1 week, then 500 mg with breakfast and evening meal for at least 1
week, then 500 mg with breakfast, lunch and evening meal; usual max. 2 g daily in divided doses.
Polycystic ovary syndrome: initially 500 mg with breakfast for 1 week, then 500 mg with breakfast and evening meal for 1 week, then 1.5-1.7 g daily in 2-3 divided doses or as directed by the physician.
Moxifloxacin + Dexamethasone
Composition:
Cinagen™-D Sterile Eye Drops: Each ml contains Moxifloxacin
Hydrochloride BP equivalent to Moxifloxacin 5 mg and Dexamethasone Sodium Phosphate USP equivalent to Dexamethasone Phosphate 1 mg.
Preservative: Sodium Perborate BP 0.001%.
Indications:
Cinagen™-D Sterile Eye Drops is indicated for the treatment of eye infections caused by susceptible microorganisms and prevention of inflammation and bacterial infection occurred after ocular surgery.
Dosage and administration:
In the prevention of infection and postoperative ocular inflammation, instill 1 drop 4 times per day. Frequency should be decreased gradually with improvement of clinical signs or as directed by the physician.
Moxifloxacin
Composition
Cinagen™ Sterile Eye Drops: Each ml contains Moxifloxacin Hydrochloride BP equivalent to Moxifloxacin 5 mg.
Indications
Cinagen™ is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of following organisms:
Aerobic gram-positive microorganism: Corynebacterium species, Micrococus luteus, Staphylococcus aureus, Staphylococus epidermis, Staphylococus haemolyticus, Staphylococcus hominis, Staphylococcus warneri, Streptococcus pneumoniae, Streptococcus viridans group Aerobic Gram-negative microorganisms: Acinetobacter iwoffi, Haemophilusinfluenzae, Haemophilus parainfluenzae.
Dosage and administration
Cinagen™ Sterile Eye Drops: One drop in the affected eyes 3 times per day for 7 days or as directed by the physician.
Montelukast
Composition:
ArokastTM4 FT: Each flash tablet contains Montelukast Sodium USP equivalent to
Montelukast 4 mg.
ArokastTM5 FT: Each flash tablet contains Montelukast Sodium USP equivalent to
Montelukast 5 mg.
ArokastTM10: Each film coated tablet contains Montelukast Sodium USP equivalent to
Montelukast 10 mg.
Pharmacology:
Montelukast is orally active and selective leukotriene receptor antagonist that inhibits the
cysteinyl leukotriene CysLT1 receptor. Cysteinyl leukotrienes and leukotriene receptor
occupation have been correlated with the pathophysiology of asthma (such as, airway
oedema, smooth muscle contraction and altered cellular activity associated with the
inflammatory process, which contribute to the signs and symptoms of asthma).
Indication:
Montelukast is indicated for the prophylaxis of asthma and management of chronic
asthma; symptomatic relief of seasonal allergic rhinitis in patients with asthma.
Dosage & Administration:
Prophylaxis of asthma:
Adult and Child over 15 years: 10 mg once daily in the evening.
Child 6-15 years: 5 mg once daily in the evening.
Child 6 months-6 years: 4 mg once daily in the evening.
Seasonal allergic rhinitis:
Adult and Child over 15 years, 10 mg once daily in the evening.
The safety and efficacy of Montelukast was demonstrated in clinical trials where it was
administered in the evening without regard to the time of food ingestion.
