Pimecrolimus INN 1%
Composition
Pmec Cream: Each gram cream contains Pimecrolimus INN 10 mg.
Indication
Pmec Cream is indicated as second-line therapy for the short-term and
noncontinuous chronic treatment of mild to moderate atopic dermatitis in
non-immunocompromised adults and children 2 years of age and older, who have failed to respond adequately to other topical prescription treatments or when those treatments are not advisable.
Dose & Administration
Skin should be cleaned before applying the cream. One finger tip unit (measured by distance from the tip of an adult index finger to the first crease of that finger) to be applied thinly and evenly on the affected area of skin twice daily. (PHYSICIAN
MAY ADJUST THE DOSE). Treatment should be stopped if signs and symptoms
(e.g. itch, rash and redness) resolve. If signs and symptoms persist and beyond 6
weeks, patients should be re-examined to confirm the diagnosis of atopic
dermatitis. A patient should not use sun lamps, tanning beds, or get treatment with
ultraviolet light therapy during treatment with Pmec Cream. Continuous long-term
use of Pimecrolimus should be avoided. A patient should not cover the skin being
treated with bandages, dressings or wraps. Loose fitting clothing that protects the
treated area from the sun are encouraged.
Potassium Citrate BP 30% & Citric Acid Monohydrate BP 5%
Kcit
Composition
Kcit™ 200 ml Oral Solution:
Each 5 ml contains:
- Potassium Citrate BP 1500 mg
- Citric Acid Monohydrate BP 250 mg
Pharmacology
Kcit Oral Solution is a stable and pleasant-tasting systemic alkalizer. Potassium Citrate is metabolized into Potassium Bicarbonate, which acts as a systemic alkalizer. It alkalinizes the urine without inducing systemic alkalosis when taken as recommended. Potassium Citrate does not neutralize gastric juice or disrupt digestion.
Indications
Kcit is indicated for:
- Relieving discomfort in urinary tract infections
- Preventing kidney stones
- Use with uricosuric agents to prevent gout
- Treating acidosis caused by kidney diseases
Dosage & Administration
- Adults: 10 ml three times daily, diluted with water
- Or as directed by the physician
Contraindications
Kcit is contraindicated in patients with:
- Severe renal impairment with oliguria or azotemia
- Untreated Addison’s disease
- Acute dehydration
- Severe myocardial damage
- Hyperkalemia of any cause
Warnings & Precautions
- Use with caution in patients with low urinary output.
- Always dilute with water to minimize gastrointestinal irritation.
- Preferably take doses after meals.
- Large doses may cause hyperkalemia or alkalosis, particularly in patients with renal impairment.
Side Effects
Kcit is generally well tolerated at recommended doses in individuals with normal renal function. However, caution is required to prevent hyperkalemia or alkalosis, especially in patients with compromised renal function. Symptoms of potassium intoxication include:
- Weakness
- Mental confusion
- Tingling in extremities
Use in Pregnancy & Lactation
There is no adequate data on the use of this product during pregnancy or lactation.
Use in Children & Adolescents
The safety and efficacy of Kcit in children and adolescents have not been established.
Drug Interactions
- Concurrent use with potassium-containing medications, potassium-sparing diuretics, ACE inhibitors, or cardiac glycosides may lead to toxicity.
Overdose
Excessive potassium intake may result in hyperkalemia, especially in patients with impaired potassium excretion. Immediate treatment includes:
- Discontinuation of potassium-containing foods and medications.
- IV administration of dextrose (10–25%) with insulin.
- Use of exchange resins, hemodialysis, or peritoneal dialysis, as needed.
Storage
- Store below 30°C, protected from light, and in a dry place.
- Keep out of reach of children.
Packing
Kcit™ 200 ml Oral Solution:
- Each box contains a 200 ml PET bottle with a 20 ml measuring cup and an insert.
Polyethylene Glycol + Propylene Glycol
Composition
Syscol Sterile Eye Drops: Each ml drops contains Polyethylene Glycol 400 USP 4 mg & Propylene Glycol BP 3 mg.
Indications
Syscol Sterile Eye Drops is indicated for the temporary relief of burning and irritation due to dryness of the eye.
Dosage and administration
Instill 1 drop 4 times daily in the affected eye (s) or as needed or as directed by the physician.
Prucalopride
Composition
Prulicon 1 Tablet: Each film coated tablet contains Prucalopride Succinate INN equivalent to Prucalopride 1 mg.
Prulicon 2 Tablet: Each film coated tablet contains Prucalopride Succinate INN equivalent to Prucalopride 2 mg.
Indication
Prucalopride is indicated for Chronic Idiopathic Constipation.
Dose & Administration
Adults (18 years of age and older): 2 mg once daily.
Elderly (over 65 years of age): 1 mg once daily.
Patients with severe renal impairment: 1 mg once daily. Should be taken with or without food or as directed by the physician.
Pregabalin
Composition
Pregan ER 82.5: Each extended release tablet contains Pregabalin BP 82.5 mg.
Pregan ER 165: Each extended release tablet contains Pregabalin BP 165 mg.
Indications
• Diabetic peripheral neuropathy
• Post-herpetic neuralgia
• Menopausal depression
Dosage & Administration
The recommended dose is Once daily. Pregabalin ER tablet should be administered once daily after an evening meal. It should be swallowed whole and should not be split, crushed or chewed.
Pizotifen
COMPOSITION :
Pizofen™ Tablet : Each film coated tablet contains Pizotifen
malate BP equivalent to Pizotifen 0.5 mg
Pizofen™ TS Tablet : Each film coated tablet contains Pizotifen
malate BP equivalent to Pizotifen 1.5 mg
INDICATION :
It is used as prophylactic treatment of vascular headaches of the migraine types, such as classic migraine, common migraine and cluster headache.
DOSE AND ADMINISTRATION :
Adult : Usually 1.5 mg daily, which may be taken as a single
dose at night or in three divided doses. Dose should be adjusted to individual patient's requirements. Upto a maximum of 4.5 mg may be given as a single dose daily.
Children : Dose is 1 mg as a single dose at night using 0.5 mg
tablet. Maximum dose is upto 1.5 mg daily usually in divided
dose.
Or as directed by the physician.
