Human Health Division (HHD) Products

Product List by Brand Name
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Lulider

Composition:
Lulider Cream: Each gram cream contains Luliconazole INN 10 mg.
Pharmacology:
Exact mechanism of action against dermatophytes is unknown.
Luliconazole appears to inhibit ergosterol synthesis by inhibiting
the enzyme lanosterol demethylase. Inhibition of this enzyme’s
activity by azoles results in decreased amount of ergosterol, a
constituent of fungal cell membranes and a corresponding
accumulation of lanosterol.
Indication:
Lulider Cream is indicated for the topical treatment of interdigital
Tinea pedis, Tinea cruris and Tinea corporis, in patients 2 years of
age and older.
Dosage & Administration:
Tinea pedis: A thin layer of cream should be applied to the
affected area and approximately 1 inch of the immediate
surrounding area(s) once daily for two weeks.
Tinea cruris and Tinea corporis: A thin layer of cream, should be
applied to the affected area and approximately 1 inch of the
immediate surrounding area(s) once daily for one week or as
directed by the physician.

Loxodol

Composition

Loxodol 4 : Each film coated tablet contains Lornoxicam INN 4 mg. Loxodol 8 : Each film-coated tablet contains Lornoxicam INN 8 mg.

Pharmacology

Lornoxicam belongs to oxicam group and non-steroidal anti-inflammatory drug (NSAID), with analgesic, anti-pyretic, anti-thrombotic and anti-inflammatory activities. Upon oral administration, lornoxicam binds to and inhibits the activity of the cyclooxygenase enzymes (COX) type 1 (COX-1) and type 2 (COX-2) by the ratio of 1:1. It readily penetrates into the synovial fluid. This leads to reduced prostaglandin and thromboxane production and decreased pain, fever and inflammation. Lornoxicam is well absorbed orally and has half-life of around 3-4 hours. The onset of action can be observed within 30 to 60 minutes of administration and eliminated via liver and kidneys ( 42%).

Indications

Indicated for the treatment of mild to moderate pain in osteoarthritis, surgery, sciatica and other inflammations.

Dosage & Administration

For Pain relief: In Adult: 8-16 mg daily in 2-3 divided doses. Max: 16 mg daily. In Osteoarthritis & Rheumatoid arthritis: Adult: 12 mg daily in 2-3 divided doses, up to 16 mg daily if needed. For patients with renal/liver impairment: Maximum 12 mg daily in 2-3 divided doses. It should be taken 1 hour before meal or 2 hours after meal to minimize gastrointestinal irritation or as directed by the physician.

Contraindications

Contraindicated in patients with peptic ulcer, severe kidney impairment and hypersensitivity. Lornoxicam can increase risk of fatal heart attack or stroke.

Warnings & Precautions

It is not recommended to administer Lornoxicam to patients with history of peptic ulcer, hypersensitivity, impaired kidney or liver function, high blood pressure, heart failure, ulcerative colitis or Crohn's disease, asthma and lupus erythematosus, diabetes or blood coagulation disorder.

Side Effects

The most common side effects are: Gastrointestinal: Abdominal pain, diarrhea, indigestion, nausea, vomiting, inflammation of pancreas and mouth ulcer. Central Nervous System: Headache, drowsiness, sleeplessness and dizziness. Eye and ENT: Visual disturbance, ringing in ear and sensitivity to light. Heart: High blood pressure, palpitations and fluid retention. Skin: Skin rash.

Use in Pregnancy & Lactation

Lornoxicam is not recommended during pregnancy and breastfeeding and is contraindicated during the last third of pregnancy.

Use in Children & Adolescents

Due to lack of data, Lornoxicam is not indicated for children and adolescents below 18 years old.

Drug Interactions

Combination with Vitamin K antagonists like warfarin increases the risk of bleeding. Combination with Cyclosporin can lead to reduced kidney function, and to acute kidney injury in rare cases. Lornoxicam can also increase the adverse effects of lithium, methotrexate and digoxin and its derivatives. The effect of diuretics, ACE inhibitors and angiotensin II receptor antagonists can be reduced, in patients with heart failure.

Overdosage

Symptoms: Increased side effects from the central nervous system and gastrointestinal tract, increased blood pressure, cardiac and / or acute renal failure. Treatment: Gastric lavage, appointment of activated carbon & monitoring of vital functions.

Storage

Store below 30°C, away from light and in a dry place. Keep all medicines out of the reach of children. Packing:

Loxodol 4 : Each box contains 3 X 10 tablets in Alu-Alu blister & an insert. Loxodol 8 : Each box contains 3 X 10 tablets in Alu-Alu blister & an insert.

Lumilast

Composition:
Lumilast Cream: Each gram cream contains Roflumilast INN 3 mg.

Indication:
Lumilast cream is indicated for topical treatment of plaque psoriasis, including intertriginous areas, in patients 12 years of age and older.

Dosage & Administration:
Lumilast cream should be applied on affected areas once daily and rubbed in completely. Hands should be washed after application, unless the cream is for treatment of the hands. Lumilast cream is for topical use only and not for ophthalmic, oral, or intravaginal use or as directed by the physician.

Loteba Eye Suspension

Composition
Loteba™ Sterile Eye Suspension: Each ml contains Loteprednol
Etabonate INN 5 mg and Tobramycin USP 3 mg.

Indications
Loteba™ is indicated for steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists. The use of a combination drug with an anti-infective component is indicated
where the risk of superficial ocular infection is high, where dangerous number of bacteria will be present in the eye.

Dosage and administration 
Shake the bottle well before use Apply 1 to 2 drops of Loteba™ into the conjunctival sac of the affected eye (s) every 4 to 6 hours. During the initial 24 to 48 hours, the dosing may be increased, to every 1 to 2 hours. Frequency should be
decreased gradually as warranted by improvement in clinical signs. Care should be taken not to discontinue therapy prematurely or as directed by the physician


Levoquin TS Eye Drops

Composition:
Levoquin  TS Sterile Eye Drops: Each ml contains Levofloxacin Hemihydrate USP equivalent Levofloxacin 15 mg.

Indications:
Levoquin TS  Sterile Eye Drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of gram-positive bacteria.

Dosage & Administration:

Levoquin TS Sterile Eye Drops:
Days 1 & 3: Instill 1 drop in the affected eye(s) every 30 minutes to 2 hours while awake per day.
Days 4 to completion: Instill 1 drop in the affected eye(s) every 1-4 hours while awake per day.
or as directed by the physician




L-Amlo

Composition
L-Amlo 1.25 Tablet:Each tablet contains Levamlodipine Maleate INN equivalent to 
Levamlodipine 1.25 mg.
L-Amlo 2.5 Tablet:Each tablet contains Levamlodipine Maleate INN equivalent to 
Levamlodipine 2.5 mg.
L-Amlo 5 Tablet:Each tablet contains Levamlodipine Maleate INN equivalent to Levamlodipine 
5 mg.

Indication
L-Amlo is a calcium channel blocker which is used alone or in combination with other 
antihypertensive agents for the treatment of hypertension. Lowering blood pressure reduces the 
risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. 

Dose & Administration
Adult recommended dose: 2.5 mg orally once daily with maximum dose 5 mg once daily. For small, fragile or elderly patients or patients with hepatic insufficiency, 1.25 mg once daily starting dose is recommended. 
Paediatric starting dose: 1.25 mg to 2.5 mg once daily or as directed by the physicians