Human Health Division (HHD) Products
Product List by Brand Name
Nabuton
Composition:
- Nabuton 500: Each film-coated tablet contains Nabumetone BP 500 mg.
- Nabuton 750: Each film-coated tablet contains Nabumetone BP 750 mg.
Indication:
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Dosage & Administration:
- Recommended starting dose: 1000 mg once daily with or without food.
- For enhanced relief, doses up to 1500–2000 mg per day may be given as a single or divided dose.
- Renal Impairment: Start with a reduced dose (500–750 mg daily) as directed by a physician.
Neumir
Composition
Neumir 2.5 Tablet : Each film coated tablet contains Mirogabalin Besylate INN equivalent to Mirogabalin 2.5 mg
Neumir 5 Tablet : Each film coated tablet contains Mirogabalin Besylate INN equivalent to Mirogabalin 5 mg
Neumir 10 Tablet : Each film coated tablet contains Mirogabalin Besylate INN equivalent to Mirogabalin 10 mg
Indications
Peripheral neuropathic pain including:
• Diabetic peripheral neuropathy
• Post-herpetic neuralgia
• Spinal pain
Dosage and Administration
Normally, the initial dose for adults is 5 mg of Mirogabalin given orally twice daily and then the dose may be gradually increased by 5 mg at an interval of at least a week to 15 mg, given orally twice daily. A dose may be adjusted appropriately between 10 mg and 15 mg depending on ages and symptoms, taken twice daily or as directed by the physician. Mirogabalin can be taken with or without food. If the patient misses a dose, he/she must take the missed dose as soon as possible. If it is almost time for the next dose, the patient should skip the missed dose and continue his/her regular dosing schedule.
Mirogabalin dosage adjustment based on renal function: No dose adjustment is recommended in mild renal impairment. Dose to be reduced to 50% in moderate renally impaired patients. A dose reduction of up to 75% required in patients with severe renal impairment and End-Stage Renal Disease.
Degree of Renal Dysfunction (Clcr: mL/min)
Mild Moderate Severe (including hemodialysis patients)
(90 > Clcr ≥ 60) (60 > Clcr ≥ 30) (30 > Clcr)
Daily dose 10 - 30 mg 5 - 15 mg 2.5 - 7.5 mg
Initial dose 5 mg twice daily 2.5 mg twice daily 2.5 mg once daily
Effective dose-
Minimum dose 10 mg twice daily 5 mg twice daily 5 mg once daily
Recommended-
dose 15 mg twice daily 7.5 mg twice daily 7.5 mg once daily
N-bion
Composition
N-bion Tablet: Each film coated tablet contains Thiamine Mononitrate USP 100 mg, Pyridoxine
Hydrochloride BP 200 mg & Cyanocobalamin BP 200 mcg.
Indications
N-bion is indicated for the treatment of B1, B6 and B12 deficiency syndrome. It is also indicated in the treatment of Polyneuropathy of any origin such as - Diabetic, Alcoholic or Toxic Neuropathies, Neuritis, Neuralgia, Cervical Syndrome, Lumbago, Sciatica, Myalgia, Intercostal Neuralgia, Herpes Zoster, Trigeminal Neuralgia, Facial Paresis.
Dosage & Administration
Ideally, 1 to 3 tablets may be administered after meal per day or as directed by the physician.
NVmet
Composition:
NVmet™ 500 Tablet: Each film coated tablet contains Metformin Hydrochloride BP 500 mg.
NVmet™ 850 Tablet: Each film coated tablet contains Metformin Hydrochloride BP 850 mg.
NVmet™ 500 SR Tablet: Each sustained release tablet contains Metformin Hydrochloride BP 500 mg.
Indication:
NVmet™, as monotherapy, is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes. NVmet™ is also indicated for use in combination with other agents, that do not result in adequate glycemic control.
Dose and administration:
Diabetes mellitus: Adult and child over 10 years initially 500 mg with breakfast for at least 1 week, then 500 mg with breakfast and evening meal for at least 1 week, then 500 mg with breakfast, lunch and evening meal; usual max. 2 g daily in divided doses.
Polycystic ovary syndrome: initially 500 mg with breakfast for 1 week, then 500 mg with breakfast and evening meal for 1 week, then 1.5-1.7 g daily in 2-3 divided doses or as directed by the physician.
Nortin
Composition:
Nortin™ 10 Capsule: Each capsule contains Nortriptyline Hydrochloride BP equivalent to 10 mg Nortriptyline.
Nortin™ 25 Capsule: Each capsule contains Nortriptyline Hydrochloride BP equivalent to 25 mg Nortriptyline.
Indication:
Depressive illness, Panic disorder & Neuropathic pain.
Dosage & administration:
Depression, low dose initially increased as necessary to 75-100 mg daily in divided doses or as a single dose (max. 150 mg daily);
Adolescent and Elderly patient : 30- 50 mg daily in divided doses. Neuropathic pain, initially 10 mg daily at night, gradually increased if
necessary to 75 mg daily; higher doses under specialist supervision. Or as directed by the physician
Navacef
Composition:
Navacef™ Paediatric Drops (15 ml): Each 1.25 ml contains Cefaclor Monohydrate USP equivalent to 125 mg of Cefaclor.
Indication
Respiratory Tract Infections: Pneumonia, bronchitis, pharyngitis, tonsillitis, otitis media.
Urinary Tract Infections: Pylonephritis, cystitis etc.
Skin & Soft Tissue Infections: Impetigo, pyoderma, cellulitis, pruritis etc.
Dosage & Administration
Adults: 250 mg three times daily (Dose should be doubled in severe cases, max. 4 g daily). Children (over 1 month): 20 mg/kg/day in three divided doses (Dose should be doubled in severe cases, max 1 g daily). 1-5 years: 125 mg three times daily.
Over 5 years: 250 mg three times daily, (Dose should be doubled in severe cases) or as directed by the physician.
Neparact TS
Composition:
Neparact™ TS Sterile Eye Suspension: Each ml contains Nepafenac INN 3 mg.
Preservative: Sodium Perborate BP 0.001%
Indications:
Neparact™ TS Sterile Eye Suspension is indicated for-
The treatment of post-operative ocular pain and
inflammation including cataract surgery.
Dosage & administration:
•Instill 1 drop once daily 1 day prior to cataract surgery
and continued on the day of surgery and through the
first 2 weeks of the post-operative period.
•An additional drop should be administered 30 to 120
minutes prior to surgery.
Nestor
Composition
Nestor 5 Tablet: Each film coated tablet contains Rosuvastatin Calcium BP equivalent to Rosuvastatin 5 mg.
Nestor 10 Tablet: Each film coated tablet contains Rosuvastatin Calcium BP equivalent to Rosuvastatin 10 mg.
Indication
• Heterozygous Hypercholesterolemia (Familial and Nonfamilial)
• Homozygous Hypercholesterolemia (Familial)
• Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
Dosage & Administration
For asian people, initial starting dose of Rosuvastatin is 5 mg once daily. The dose of Rosuvastatin is 5-40 mg once daily. Heterozygous Hypercholesterolemia (Familial and Nonfamilial) and Mixed Dyslipidemia (Fredrickson Type IIa and IIb) the usual recommended starting dose of rosuvastatin is 10 mg once daily or as directed by the physician.
Navix Plus
Composition:
Navix™ Plus Tablet: Each film coated tablet contains Clopidogrel Bisulfate USP equivalent to Clopidogrel 75 mg and Aspirin BP 75 mg.
Indication:
The preparation is used for the prevention of ischemic events, myocardial infarction, stroke and cardiovascular death in patients with acute coronary syndrome.
Dosage & Administration:
The recommended dose is once daily or as directed by the physician.
Navix
Composition:
Navix™ Tablet: Each film coated tablet contains Clopidogrel Bisulfate USP equivalent to 75 mg Clopidogrel.
Indication:
Clopidogrel is indicated for the reduction of atherosclerotic events (myocardial infarction, stroke and vascular death) and in patient with atherosclerosis documented recent stroke, recent myocardial infarction or established peripheral arterial disease (PAD).
Dosage & Administration:
The recommended dose of Clopidogrel is 75 mg once daily with or without food. No dosage adjustment is required for elderly patients or patients with renal disease or as directed by the physician.
Nafgal
Composition:
Nafgal Cream: Each gram cream contains Naftifine Hydrochloride USP 20 mg.
Indications:
Nafgal Cream is indicated for the treatment of interdigital tinea pedis, tinea cruris and tinea corporis caused by the organism Trichophyton rubrum.
Dosage & Administration:
Apply a thin layer of Nafgal Cream once-daily to the affected areas plus half inch margin of healthy surrounding skin for 2 weeks or as directed by the physician.
